Abstract

The endotoxin adsorption method (PMX-DHP: Toray Industries, Inc., Tokyo, Japan) is used for treatment of patients with sepsis and septic shock primarily caused by Gram-negative infections in Japan. Procalcitonin (PCT) levels may be a good marker of infection and levels exceeding 10 ng/ml occur almost exclusively in severe sepsis. The aim of this study was to evaluate PMX-DHP for severe sepsis or septic shock patients according to PCT values. Patients were classified as a group in which PCT is higher than 10 ng/ml (H group) or a group in which PCT is lower than 10 ng/ml (L group).

Highlights

  • Community-acquired pneumonia remains a common ventilation (MV) were randomized into two groups: one group was condition worldwide

  • This study shows that the inhibition of the intramyocardial expression of tumour necrosis factor (TNF)-α and of its secondary mediator COX-2 related to moderate hypothermia during cardiopulmonary bypass (CPB) is associated with the inhibition of p38 mitogen-activated protein kinase (MAPK)–acute pancreatitis (AP)-1, but not of the NF-κB pathway

  • Purification, characterization, and analytical mass assignment of inducible nitric oxide synthase (iNOS) from DLD-1-5B2 cells are in progress to provide mass standardization for the iNOS immunoassay

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Summary

Introduction

Community-acquired pneumonia remains a common ventilation (MV) were randomized into two groups: one group was condition worldwide. Methods Eighty-one consecutive patients (age 63 ± 16 years, male n = 51, SAPS 2 score 49 ± 11, mechanical ventilation n = 50, vasopressors n = 56, renal failure n = 19, postoperative n = 23) admitted to the ICU during a 3-month period were evaluated. Probiotics administration was suggested to reduce the incidence of infections and the overall morbidity and mortality in surgical patients The aim of this prospective randomized clinical trial was to assess the effects of a combination formula of probiotics and prebiotics (Synbiotic 2000Forte; Medifarm, Sweden) versus prebiotics only (fiber) in critically ill, long-term mechanically ventilated trauma patients. This study examines the acute patient outcomes associated with the evolution of early total care to damage control orthopaedics for multiply injured patients with femoral shaft fractures

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