Endoskopik olarak tanımlanan gastrit ile histolojik bulgular arasındaki ilişki

Abstract

Background and Aims: Gastritis refers to macroscopic changes in the gastric mucosa. A correlation between macroscopic and microscopic features of gastritis has not yet been adequately established. In this study, we aimed to expose the relationship between endoscopic appearance and histological findings in gastritis patients. Materials and Methods: One hundred thirty-one patients who had upper gastrointestinal system endoscopy for dyspepsia between January 2004 and March 2005 were enrolled in this study. Endoscopic classification of gastritis was performed according to the Sydney system. Two samples from both antrum and corpus were obtained by standard size biopsy forceps. Histological examination was performed by an expert gastrointestinal pathologist according to the Sydney system. Results: There was a statistically significant relation between endoscopic erythematous appearance of the corpus and presence of Helicobacter pylori (p=0.031), atrophy (p=0.000) and activation (p=0.001). There was also a statistically significant relation between endoscopic edematous appearance and histological presence of Helicobacter pylori (p=0.03). There was no statistically significant relation between endoscopic erythematous appearance of the antrum and presence of inflammation (p=0.24), Helicobacter pylori (p=0.29), atrophy (p=0.72), activation (p=0.57), or metaplasia (p=0.76). Conclusions: The appearance of erythema in the corpus is a valuable marker for the histological presence of Helicobacter pylori gastritis, activity and atrophy.