Abstract
Endoscopic ultrasound (EUS) has evolved from being primarily a diagnostic modality into an interventional endoscopic tool for the management of both benign and malignant gastrointestinal illnesses. EUS-guided therapy has garnered particular interest as a minimally invasive approach for the treatment of pancreatic cancer, a disease often complicated by its aggressive course and poor survival. The potential advantage of an EUS-guided approach revolves around real-time imaging for targeted therapy of a difficult to reach organ. In this review, we focus on EUS-guided therapies for pancreatic neoplasms.
Highlights
Since its introduction over 30 years ago, endoscopic ultrasound (EUS) has evolved from being primarily a diagnostic tool into a therapeutic modality for various gastrointestinal diseases
EUS-guided fineneedle aspiration (EUS-FNA) is a well-established minimally invasive procedure that has been increasingly used for the investigation and staging of pancreatic neoplasms due to its favorable performance and safety profile when compared with other extracorporeal tissue acquisition techniques [3]
The ability to accurately and safely introduce a needle into a deeply located retroperitoneal organ serves as a vehicle for localized treatment. This is the basis for EUS-guided fine-needle injection (EUS-FNI) for pancreatic neoplasms: a safe, minimally invasive approach, with real-time imaging to selectively access deeply located targets and provide localized therapy
Summary
Since its introduction over 30 years ago, endoscopic ultrasound (EUS) has evolved from being primarily a diagnostic tool into a therapeutic modality for various gastrointestinal diseases. This transition towards “interventional EUS” has been facilitated by the advancement of curvilinear-array endoscopes and peripheral devices [1, 2]. The ability to accurately and safely introduce a needle into a deeply located retroperitoneal organ (i.e., pancreas) serves as a vehicle for localized treatment This is the basis for EUS-guided fine-needle injection (EUS-FNI) for pancreatic neoplasms: a safe, minimally invasive approach, with real-time imaging to selectively access deeply located targets and provide localized therapy. We focus on advances of EUS-guided therapeutic approaches for pancreatic neoplasms
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