Endoscopic iodine staining for clinical investigation of esophageal disease screening in Huai′an of Jiangsu Province with a survey of 1983 cases

Abstract

Objective To investigate the important clinical value of endoscopic iodine staining in endoscopic screening of esophageal early cancer in high incidence area of esophageal cancer. Methods Endoscopic esophageal cancer screening was performed on 1 983 patients aged 40-60 years in Wudun Town and Yanhe Town, Qingpu District, Huai′an City of Jiangsu Province.The color and morphology of esophageal mucosa were compared before and after iodine staining, and biopsy was performed on abnormal mucosa staining. Results A total of 835 lesions in 740 patients underwent esophageal biopsy, 273 were found before iodine staining(white light), and 562 were found after iodine staining.Among them, 5 cases of intramucosal carcinoma and 205 cases of dysplasia were found after iodine staining.The difference between the two groups was statistically significant(P<0.05), which indicated that the detection rate of esophageal cancer and precancerous lesions after iodine staining was significantly higher than that before staining. Conclusion Endoscopic iodine staining of esophageal mucosa can significantly improve the detection rate of esophageal cancer and precancerous lesions during screening.Because of its low price and simple operation, it is worthy of clinical application. Key words: Esophageal cancer; Endoscopy; Iodine staining