Abstract
Objective To evaluate narrow-band imaging(NBI)for early esophageal cancer and precancerous lesions. Methods A total of 170 patients (192 lesions) diagnosed as having superficial esophageal carcinoma and precancerous lesions by endoscopy were retrospectively analyzed. Clinical data of endoscopy, narrow-band imaging (NBI) and iodine chromoscopy were analyzed. Results The detection rates of early esophageal cancer were both 100.0% in NBI(13/13) and iodine staining (13/13), with no statistically significant difference (P>0.05). The detection rate of high grade intraepithelial neoplasia in NBI and iodine staining was 94.9% (94/99) and 100.0% (99/99) respectively with no statistically significant difference (P>0.05); The detection rate of low grade intraepithelial neoplasia in iodine staining was 100.0% (80/80), significantly higher than that of NBI 78.8% (63/80) (P<0.01). Conclusion NBI and iodine staining endoscopy show better diagnostic value for early esophageal cancer and similar diagnostic value for high grade intraepithelial neoplasia in precancerous lesions. But for the low grade intraepithelial neoplasia, the diagnostic value of iodine staining endoscopy is better than that of NBI. Key words: Esophageal neoplasms; Precancerous lesion; Staining and labeling; Endoscopy; Narrow-band imaging
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