Endometrial cancer and hormonal therapy (HT)

Abstract

Endocervical margins affected: 44 (15.7%): pre: 32 (14.2%) postmenopausal: 12 (21.8%). Reconizations 17 (6%): premenopausal: 14 (6.2%). Postmenopausal: 3 (5.4%). Hysterectomy postcone: 11 (3.9%): premenopausal: 3 (1.3%). Postmenopausal: 8 (14.5%) hysterectomy indications: 3 microinvasive, 3 persistence CIN 2–3 postcone, 5 Adeno insitu. Conclusions: We found no difference between the 2 groups of preand postmenopausal women in terms of cone histology and number of reconizations made. In the group of postmenopausal women, we found a large number of endocervical margins affected in the histological study of cone and this result would correspond to a greater number of endocervical lesions in menopausal than in premenopausal women. The other major difference was in the postcone hysterectomies related to high-grade lesions with large endocervical affection, which reach a rate of 15%.