Endometrial Biopsy Audit and its Clinico-Pathological Correlation in Patients with Abnormal Uterine Bleeding in a Zonal Care Centre

Abstract

Background: Abnormal uterine bleeding is the commonest problem affecting premenopausal, perimenopausal,and postmenopausal females and is the most common cause of the premalignant and malignant endometriallesions resulting in endometrial samples.Aim & Objective: To study the clinicopathological correlation of abnormal uterine bleeding in premenopausal,perimenopausal, and postmenopausal female.Material and methods: The retrospective study was conducted in the Military Hospital, Allahabad (UP), by theDepartment of Pathology from Aug 2021 to Aug 2022. A total of 135 patients who presented with abnormal uterinebleeding were studied.Results: The age of the patients ranged from 20 to 70 years in the study. There were a total of 63 cases in the agegroup of 41 to 50 years. The major bleeding pattern observed was menorrhagia, followed by post menopausalbleeding, polymenorrhagia, metrorrhagia, oligomenorrhagia, and menometrorrhagia. The histopathologicalpatterns observed in abnormal uterine bleeding were proliferative phase endometrium, followed by secretaryphase, disordered proliferative phase, endometrial hyperplasia, atropic endometrium, malignancy, andinadequate.Conclusion: Endometrial biopsies are the first line diagnostic tool for diagnosing endometrial pathology becauseof its diagnostic accuracy, safety, quickness, and convenience. But lesion such as leiomyoma and adenomyosiscan be missed..