Endogenous nitroso compounds (NOC) from dietary source: Plausible promoters of oral carcinogenesis in non-smokers and non-alcoholics

Abstract

Goal of the perspectiveEndogenous nitroso compounds (NOCs) from food sources contribute to oral carcinogenesis in non-smokers and non-alcoholics. Research in this field may lead to improved preventative and intervention methods for treating oral cancer in those who are not exposed to conventional risk factors like alcoholism and smoking. DiscussionThe intricate interplay between endogenous nitroso compounds, oral microbiota, and the host's immune response presents a complex landscape in understanding the promotion of oral carcinogenesis in non-smokers and non-alcoholics. Insights gained from these research efforts hold the potential to comprehensively understand the mechanisms through which NOCs contribute to oral carcinogenesis. Identification of specific molecular and cellular pathways through which NOCs from dietary sources contribute to oral carcinogenesis are crucial to establish the role of Endogenous NOCs. ConclusionThe field of study on endogenous NOCs derived from diet and their potential impact on oral carcinogenesis in individuals who do not smoke or drink is a dynamic and constantly changing one. In-depth research is vital to create specialized/customised prevention and treatment plans for this category of oral cancer.