Abstract
Radiation lung injury typically occurs after treatment for malignancies, including lung, esophagus, breast, and hematopoietic malignancies. The risk has decreased with development of radiation treatment with lower doses to lung fields via intensity modulated and stereotactic procedures. The risk is still substantial in some settings, such as total body radiation in patients with stem cell transplants or stem cell transplants in patients with recurrent Hodgkin lymphoma. Histologically, radiation injury progresses from acute alveolar injury (diffuse alveolar damage) through a fibrotic phase resembling nonspecific interstitial pneumonia. The histologic features are nonspecific, but atypical pneumocytes are especially enlarged and bizarre in the acute and subacute phases of radiation-induced lung injury. We present a case of radiation fibrosis requiring transplant in a patient with relapsing mediastinal Hodgkin lymphoma requiring stem cell transplant and repeat mediastinal radiation.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
