Enantioselective synthesis of (+)-patulolide C via proline-catalyzed sequential α-aminooxylation and Horner–Wadsworth–Emmons olefination

Gowravaram Sabitha,J.S Yadav,G Chandrashekhar,K Yadagiri

doi:10.1016/j.tetlet.2010.05.063

Enantioselective synthesis of (+)-patulolide C via proline-catalyzed sequential α-aminooxylation and Horner–Wadsworth–Emmons olefination

Gowravaram Sabitha, J.S Yadav + Show 2 more

https://doi.org/10.1016/j.tetlet.2010.05.063

Copy DOI

Journal: Tetrahedron Letters	Publication Date: May 21, 2010
Citations: 26

Affiliation: Indian Institute of Chemical Technology

#Horner Wadsworth Emmons Olefination #Emmons Olefination + Show 8 more

Abstract
Full-Text PDF
Similar Papers

Abstract

Abstract The enantioselective total synthesis of (+)-patulolide C isolated from Penicillium urticae has been achieved from commercially available 9-decen-1-ol. Jacobsen’s kinetic resolution and sequential α-aminooxylation and Horner–Wadsworth–Emmons (HWE) olefination followed by Yamaguchi lactonization are used as the key reaction steps.

Full Text