Abstract
The enantioselective synthesis of 2-[5-(9 H-purin-9-yl)-2-cyclopenten-1-yl]ethanol analogues is described. (1R,5R)-[1-( tert-butyldimethylsilyloxy)ethyl]-2-cyclopenten-5-ol 4a and (1S,5S)-[1-( tert-butyldimethylsilyloxy)ethyl]-2-cyclopenten-5-ol 4b were coupled with 6-chloropurine and 2-amino-6-chloropurine using Mitsunobu reaction conditions. Compounds 6a & b, 7a & b, 8a & b, 9a & b, and 10a & b were tested for antiviral activity.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
