Enantioselective Potentiometric Membrane Eectrodes Based on α-, β- and γ-Cyclodextrins as Chiral Selectors for the Assay of S-Deprenyl

Abstract

Enantioselective, potentiometric membrane electrodes (EPMEs) based on � -, � - and � -cyclodextrins (CDs) as chiral selectors were proposed for the assay of S-deprenyl. The response characteristics proved that the proposed EPMEs could be reliably used in the assay of S-deprenyl. The best slope is exhibited by the EPME based on � -cyclodextrin. The limits of detection are very low: 10 -9 mol L -1 magnitude order for � -cyclodextrin based EPME, and 10 -11 mol L -1 magnitude order for � -, and � -cyclodextrins based EPMEs. The surfaces of the electrodes are stable and easily renewable by polishing on alumina paper.