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https://doi.org/10.1055/a-2039-6352
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Cite Journal: Synlett |  Publication Date: Mar 13, 2023 |
Affiliation: Doshisha Women's College of Liberal Arts
AbstractA chiral lithium amide mediated enantioselective [2,3]-Wittig rearrangement of carboxylic acid enolate has been developed. The reaction proceeds through the formation of a chiral mixed aggregate that shields one enantioface of enolate anion to give a highly functionalized chiral α-hydroxycarboxylic acid.
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