Abstract
Structurally simple enantiopure thioureas were used as chiral solvating agent (CSA) for the rapid determination of enantiomeric purity of chiral carboxylic acids by 1H NMR spectroscopy in the presence of DMAP. The formation of diasteromeric complexes between the enantiopure thiourea and carboxylate-DMAPH+ ion pair gave rise to well-resolved 1H NMR signals of the enantiomers of carboxylic acids. Furthermore, thiourea S,S-1 was used to assign the absolute configuration of mandelic acid.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
