Abstract

ABSTRACTOur choices around consumer products directly influence our amount of chemical exposure. Although access to chemicals within individual products are available, we often use multiple products so ingredient names must be harmonized to accurately estimate cumulative exposure. We evaluated the accuracy and coverage of two strategies, PubChem and tmChem, with respect to a database of 55K products. More than half of the ingredients identified by PubChem were specific chemical names (55%), followed by natural or artificial colors (20%) and plants or plant derivatives (13%). The majority of ingredients identified by tmChem were chemical names (83.9%). Only 1,696 of the 8,247 (20.56%) were identified by both systems. Although tmChem had better coverage, ~70% of ingredients identified by tmChem need further work to align with a specific chemical. Both strategies are needed to provide an accurate, personalized, and cumulative measure of chemical exposure.

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