Abstract

Depression is a clinical disease, mainly accompanied by mood or emotional abnormalities, mainly depression, slow thinking, often accompanied by emotional abnormalities, cognitive behavior, psychophysiological and interpersonal changes or disorders. Here, using static and task-state MRI data, we present a comprehensive study of abnormal neural activity in patients with depression through spatiotemporal, static, and dynamic measures, demonstrating its validity as an underlying biological trait. In order to effectively study the role of emotion regulation in depression, a brain dynamic network synthesis method based on support vector machine model and community detection algorithm was established. We selected data on the mental state of 45 patients from a hospital’s psychiatric disease control center. They had no history of hearing impairment and normal (or corrected) vision. All procedures are agreed in writing by each participant. The results show that this method can effectively reduce the depression degree of the subjects, and the multi-level features of the integration of task activation and task regulation connection reach 81% ( < 0.0010, surrogate test) and 83% (<0.0016, surrogate test), respectively. The recovery of its depressive psychological state has a significant impact. Numerous studies have used various forms of emotional stimuli to reveal abnormal behaviors and neural responses in multi-channel emotional processing in patients with depression, providing valuable insights into the mechanism of multi-channel emotion regulation in depression.

Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call