Abstract

Levels of α(1 → 3)- l-fucosyltransferase activities were measured in salivas of patients with ovarian cancer. GDP- l-Fuc : GlcNAc α(1 → 3)-fucosyltransferase was found elevated in patients known to have epithelial ovarian cancer, irrespective of their ABH and Lewis blood group phenotypes. GDP- l-Fuc : Glc α(1 → 3)-fucosyltransferase was also elevated in both Lewis positive and negative patients, although the enzyme activity was very low or absent in Lewis negative healthy controls.

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