Electroosmotic Flow Induced Lift Forces on Polymer Chains in Nanochannels.

Abstract

A major objective of research in nanofluidics is to achieve better selectivity in manipulating the fluxes of nano-objects and in particular of biopolymers. Numerical simulations allow one to better understand the physical mechanisms at play in such situations. We performed hybrid mesoscale simulations to investigate the properties of polymers under flows in slit pores at the nanoscale. We use multiparticle collision dynamics, an algorithm that includes hydrodynamics and thermal fluctuations, to investigate the properties of fully flexible and stiff polymers under several types of flow, showing that Poiseuille flows and electroosmotic flows can lead to quantitatively and qualitatively different behaviors of the chain. In particular, a counterintuitive phenomenon occurs in the presence of an electroosmotic flow: When the monomers are attracted by the solid surfaces through van der Waals forces, shear-induced forces lead to a stronger repulsion of the polymers from these surfaces. Such focusing of the chain in the middle of the channel increases its flowing velocity, a phenomenon that may be exploited to separate different types of polymers.