Abstract

Here, we present electronic-type biosensors for ultra-sensitive detection of pancreatic cancer cells, based on graphene field effect transistors. The devices was decorated with bi-functional pyrene-iRGD peptides in which the pyrene moiety binds to the graphene though pi-pi interaction and the iRGD peptides binds to neuropilin receptors in the pancreatic cancer cells. Real-time electronic detection enabled detecting few cancer cells in the presence of the human serum, which is a critical for the early detection of cancer diagnosis and treatments. We acknowledge the support of ND EPSCoR New Faculty Award and ND NASA EPSCoR RID Grant.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.