Abstract
Chorioallantoic membranes were examined electron microscopically at varied intervals after inoculation with fowlpox virus. At 2 hours, adsorption and phagocytosis of particles by ectodermal cells were observed. Following a latent period of approximately 46 hours, areas of “reticulogranular” material were present associated with membranes which appeared to be forming immature viral particles. In addition, occasional nuclei contained mature particles and unusual membrane configurations. Inclusion bodies were formed from lipid granules, and it appeared that one of the function of the inclusions might be the elaboration of an outer layer for the viral particles. Release of mature particles from the cells was accomplished by a process of budding from the cell surface.
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