Abstract
The electrochemical oxidation of uric acid has been studied in 0.50 M NaCl and phosphate buffers of ionic strength 0.05 to 0.5 M. The kinetics of the decay of UV-absorbing intermediate generated during electrooxidation of uric acid (7,9-dihydro-1H-purine-2,6,8-(3H)-trione) has also been studied. On the basis of pseudo first order rate constants observed in different media, it has been concluded that the diimine species formed from the 2e, 2H+ oxidation of uric acid is attacked by water to give diol, which then decomposes in a series of reactions to give allantoin as the major product at pH 7.2. The possibility of attack by phosphate on diimine has been ruled out.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call