Abstract
In this study, differential pulse stripping voltammetry meat tissues examined three drug residues salbutamol and ractopamine hydrochloride oxidation peak on the glassy carbon electrode serious overlapping and partially overlapping with clenbuterol, among the three components there is a strong interaction, the mixture is difficult to determine the content of each single component directly. Based on the optimization of the experimental conditions and based on the introduction Chemometrics mixing its components resolved to avoid the tedious separation and purification steps, simplifying the measurement process.
Highlights
With large-scale animal husbandry towards the development of livestock breeding are becoming increasingly mixed together, leading to cross contamination between a variety of different viruses and bacteria, making the prevention of animal diseases increases the difficulty, in the early stages, the main discovery of antibiotics on farmed prevent bacteria and viruses have a very good effect, thereby breeding owners widespread use of antibiotics for prevention of animal diseases (Ni et al, 2006)
Some unscrupulous companies are seriously overweight leads to the overuse of antibiotics in animal’s residues that do not meet national food safety regulations and regulations on food import and export trade of the country, to the main farming, and to the country to bring considerable losses (Fang and Chen, 2007)
Materials: Electrical sensitivity and accuracy of analytical chemistry methods are high, with good selectivity, easy operation, fast analysis, features a wide range of applications, especially in the modern instrumental analysis and computer combined with automated analytical work
Summary
With large-scale animal husbandry towards the development of livestock breeding are becoming increasingly mixed together, leading to cross contamination between a variety of different viruses and bacteria, making the prevention of animal diseases increases the difficulty, in the early stages, the main discovery of antibiotics on farmed prevent bacteria and viruses have a very good effect, thereby breeding owners widespread use of antibiotics for prevention of animal diseases (Ni et al, 2006). With the widespread use of antibiotics, many new problems were discovered, such as their side effects and drug resistance of animals. Clenbuterol as a best agonist, selectively acts on the adrenal receptors at therapeutic doses, has the effect of relaxation of airway smooth muscle for the treatment of asthma to animals fed feed containing clenbuterol, the animal can activate adenosine cyclase enhance lipolysis and promote animal muscle, skeletal muscle protein synthesis to accelerate animal growth rate, increase lean (Zou and Mo, 1997). U.S Food and Drug Administration and the World Health Organization recommend clenbuterol in animal tissue MRLs for: Meat 0.2 ug/Kg, liver 0.6 ug/Kg, kidney 0.6 ug/Kg, fat 0.2 ug/Kg, milk 0.05 ug/Kg
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