Abstract
Due to their likeness in composition to natural tissues, synthetic hydroxyapatite (HA) nanoparticles have good biocompatibility, bioactivity, and osteoconductivity and have large applicability in a wide range of fields such as in tissue replacement, drug/gene delivery carriers, and biocompatible coatings. In this study, we synthesize hydroxyapatite by double decomposition method, we carried out the reactions in a water–ethanol medium at pH = 12 and room temperature. Its ceramization and the effect of sintering temperature and forming technique of this ceramic on the chemical and structural behavior, and compare it to natural hydroxyapatite extracted from bovine bones. According to the results obtained from the structural and morphological characterization techniques, the elaborate hydroxyapatite is similar to natural hydroxyapatite and can be used as a bone substitute. The HA powders obtained are modified by different levels of polyethylene. The characterization by different techniques (infrared; DRX; SEM, etc.). All the results of this work allow on the possibility of using these materials in the biomedical field such as in tissue replacement, drug/delivery carriers.
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