Ejaculatory duct dysfunction and chronic pelvic pain syndrome in men

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Chronic pelvic pain syndrome (CPPS) describes unexplained pelvic pain in men associated with irritative voiding symptoms, post-orgasmic pain, and/or pain located in the groin, genitalia, or perineum in the absence of bacterial infection. Many different etiologies of CPPS have been proposed, including roles for immunologic, neurologic, endocrine, and psychologic factors. This article examines one such factor—ejaculatory duct obstruction (EDO). Because EDO is correctable with relatively minor surgery, it should be considered by any clinician caring for a patient who reports symptoms of CPPS.