Abstract

Helical geometries have been used in recent years to form cardiovascular prostheses such as stents and shunts. The helical geometry has been found to induce swirling flow, promoting in-plane mixing. This is hypothesised to reduce the formation of thrombosis and neo-intimal hyperplasia, in turn improving device patency and reducing re-implantation rates. In this paper we investigate whether joining together two helical geometries, of differing helical radii, in a repeating sequence, can produce significant gains in mixing effectiveness, by embodying a ‘streamline crossing’ flow environment. Since the computational cost of calculating particle trajectories over extended domains is high, in this work we devised a procedure for efficiently exploring the large parameter space of possible geometry combinations. Velocity fields for the single geometries were first obtained using the spectral/hp element method. These were then discontinuously concatenated, in series, for the particle tracking based mixing analysis of the combined geometry. Full computations of the most promising combined geometries were then performed. Mixing efficiency was evaluated quantitatively using Poincaré sections, particle residence time data, and information entropy. Excellent agreement was found between the idealised (concatenated flow field) and the full simulations of mixing performance, revealing that a strict discontinuity between velocity fields is not required for mixing enhancement, via streamline crossing, to occur. Optimal mixing was found to occur for the combination R = 0.2 D and R = 0.5 D , producing a 70 % increase in mixing, compared with standard single helical designs. The findings of this work point to the benefits of swirl disruption and suggest concatenation as an efficient means to determine optimal configurations of repeating geometries for future designs of vascular prostheses.

Highlights

  • Helical pipe based geometries have been previously investigated for their ability to generate swirling flow and in-plane mixing [1,2]

  • These flow attributes are thought to be beneficial in preventing the formation of thrombosis within vascular prostheses, as well as reducing neo-intimal hyperplasia near to the graft anastomoses

  • Helical geometries have been previously proposed and tested for use as vascular prostheses such as shunts and stents, due to the swirling flow and in-plane mixing that are induced by the helical geometry, which are thought to reduce thrombosis and neo-intimal hyperplasia

Read more

Summary

Introduction

Helical pipe based geometries have been previously investigated for their ability to generate swirling flow and in-plane mixing [1,2]. These flow attributes are thought to be beneficial in preventing the formation of thrombosis within vascular prostheses, as well as reducing neo-intimal hyperplasia near to the graft anastomoses. Though internal mammal artery grafts are achieving patency rates of. 90–95% after 15 years, saphenous vein grafts have patency rates of only roughly 50% after 10 years [3]. As of 2009 the one and two-year cumulative patency rates for expanded polytetrafluoroethylene (ePTFE) vascular access grafts are 59–90% and 47–85% respectively, in the Fluids 2019, 4, 59; doi:10.3390/fluids4020059 www.mdpi.com/journal/fluids

Methods
Results
Conclusion
Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.