Abstract
AbstractMonofluorinated epoxides were successfully prepared through the O‐cyclization reaction between α‐fluorosulfoximines and ketones. The obtained fluoroepoxides were found to readily undergo an interesting ring‐opening process (involving both a CF bond cleavage and another CF bond formation) in the presence of titanium tetrafluoride or pyridinium poly(hydrogen fluoride) to afford α‐fluorinated ketones. The later process constitutes a formal catalytic 1,2‐fluorine shift reaction.
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