Abstract
Acetic acid is one of the important weak acids which had long history in chemical industries. This weak organic acid has been widely used as one of the key intermediate for many chemical, detergent, wood and food industries. The production of this acid is mainly carried out using submerged fermentation system and the standard strainAcetobacter aceti. In the present work, six different media were chosen from the literatures and tested for acetic acid production. The highest acetic acid production was produced in medium composed of glucose, yeast extract and peptone. The composition of this medium was optimized by changing the concentration of medium components. The optimized medium was composed of (g/L): glucose, 100; yeast extract, 12 and peptone 5 and yielded 53 g/L acetic acid in shake flask after 144 h fermentation. Further optimization in the production process was achieved by transferring the process to semi-industrial scale 16-L stirred tank bioreactor and cultivation under controlled pH condition. Under fully aerobic conditions, the production of acetic acid reached maximal concentration of about 76 g/L and 51 g/L for uncontrolled and controlled pH cultures, respectively.
Highlights
Acetic acid (CH3COOH) is one of the simplest organic carboxylic acid
The best medium for acetic acid production was composed of (g/L): glucose; 30, yeast extract; 5, and peptone; 2. This obviously shows that, this medium has a high amount of carbon sources in form of glucose and supported high acetic acid production
The higher amount of carbon source, the high concentration of acetic acid can be produced. Acetic acid bacteria such as Acetobacter responded insensitive to the glucose and only somewhat sensitive in the presence of glycerol[15]
Summary
Acetic acid (CH3COOH) is one of the simplest organic carboxylic acid This colourless weak acid is characterized by distinctive sour taste and pungent smell. Nowadays, this acid is considered as one of the key intermediate for many industries including: chemical, HESHAM A. Acetic acid is an important as intermediate compound for the industrial production of different chemicals such as vinyl acetate polymer, cellulose acetate, terephthalic acid, dimethyl terephthalate, acetic acid esters/acetic anhydride and calcium magnesium acetate. All these products are made from petroleum-derived acetic acid[1]
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