Abstract
AbstractThe synthesis of enantiomerically pure cis‐ and trans‐limonene oxides and their corresponding diols from easily accessible raw materials has been of much interest for a long time. A straightforward one‐step biocatalytic resolution of the (+)‐cis/trans limonene oxide and the (−)‐cis/trans‐limonene oxide has been investigated. Epoxide hydrolases showing complementary stereoselectivity were recombinantly expressed in Escherichia coli, which allowed easy purification. The conditions for the selective epoxide hydrolase catalyzed ring‐opening reactions have been optimized and enabled the preparation of all limonene oxide enantiomers. The described utilization of recombinant epoxide hydrolases for the synthesis of all limonene oxide enantiomers was superior to chemical routes and represents a highly resource‐efficient one‐step preparation.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
