Abstract
Analysis of the treatment of type-1 diabetes in children and adolescents in recent years has shown a significant increase in using of insulin analogues. Improvement in the compensation of carbohydrate metabolism and state of microcirculation on the background of the use of insulin analogues when compared with other insulin drugs is shown. The importance of maintaining stable blood glucose levels at night to prevent the development of microcirculatory disorders, which is ensured, primarily by the drugs of non-peak prolonged insulin action was proved.
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