Efficacy of zirconium oxide nanoparticles coated on stainless steel and nickel titanium wires in orthodontic treatment.

Abirami Selvaraj

doi:10.6026/97320630017760

Abstract

It is of particular intrigue to synthesize, analyze anti-bacterial, anti-inflammatory activity, cytotoxicity effect of clove and cardamom reinforced zirconium oxide nanoparticles to coat the orthodontic archwires and study its ramifications. Characterization of nanoparticles was done using Transmission electron microscopic analysis (TEM). Antimicrobial activity was assessed using agar well diffusion method. Cytotoxic effect was assessed using Brine Shrimp Assay. Anti-inflammatory activity was completed using Bovine Serum Albumin (BSA). A Digital magnetic stirrer with a hot plate was used to coat orthodontic arch wires such as NiTi and SS. TEM spherical shape was of size 5 -20 nm. Minimal cytotoxicity was observed at 50 µL. Anti-inflammatory property was fair. Antimicrobial activity against Lactobacillus species, streptococcus mutans staphylococcus aureus and Candida albicans was recorded. NiTi and SS showed a colour shift from silver to orange red with a uniform surface coating on wires. Thus, green synthesized zirconium oxide nanoparticles have potent antimicrobial, anti-inflammatory properties with minimal cytotoxicity for further consideration as nano-coatings on orthodontic archwires such as NiTi and Stainless Steel.

Highlights

One of the greatest challenges in orthodontic biomechanics is to minimize the friction, which occurs at a number of points along the archwire
As a bracket slides along an archwire, friction is only a small part of the resistance to tooth movement known as resistance to sliding (RS) [2,3]
UV-vis spectroscopy: demonstrated that all naupliis were able to survive at all UV-VIS spectroscopic analysis, which showed a peak at 430 nm concentrations except at 50 μL there was a death of 10% of of visible spectrum by reduction of zirconium, salts to ZrO2 NP’s nauplii

Summary

Background

One of the greatest challenges in orthodontic biomechanics is to minimize the friction, which occurs at a number of points along the archwire. As a bracket slides along an archwire, friction is only a small part of the resistance to tooth movement known as resistance to sliding (RS) [2,3]. The three components of RS: (1) Friction, static or kinetic (FR) (contact between wire and bracket surfaces), (2) binding (BI), which happens when the tooth tips or the wire bends until the wire contacts the bracket edges, and (3) notching (NO), which occurs when the wire deforms permanently at the wire-bracket corner interface [3]. To 60% orthodontic forces is required to move a tooth as well as cytotoxicity effect of clove and cardamom reinforced zirconium overcome friction in bracket-archwire interface. Raises the risk of root resorption and anchorage loss [4,5,6]

Materials and Methods

Discussion

Limitations

Findings

Conclusion