Abstract

Objective: To evaluate the efficacy of Yiqi Fumai freeze-dry powder (YFP) on ischemic diastolic heart failure. Methods: 100 patients diagnosed with unstable angina accompanying ischemic diastolic heart failure (IDHF) were selected randomly. 52 patients with TCM syndrome of qi-yin deficiency were divided into Chinese and Western combination therapy group. 48 patients have no TCM syndrome of qi-yin deficiency, and were treated with standard western medicine. After treatment, Seattle Angina Questionnaire Evaluation, ECG, conventional and stress echocardiography (SE) index, NT-proBNP were compared between before and after treatment. Results: The differences of PL, TS, DP between before and after treatment by YFP were statistically significant (P

Highlights

  • Cardiovascular events are major fatal disease in China

  • The Yiqi Fumai freeze-dry powder (YFP) was here prepared based on the traditional Chinese medicine (TCM) formula of pulse-activating powder using modern production technology refined for formulation of modern Chinese medicine

  • The Seattle Angina Scale (SAQ), ECG, stress echocardiography and amino-terminal pro-brain natriuretic peptide precursor (NT-proBNP) were used to assess the efficiency of YFP which was based on pulse-activating powder

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Summary

Introduction

Cardiovascular events are major fatal disease in China. Acute myocardial infarction (AMI) and ischemic heart. Coronary heart disease is divided into two categories, thoracic obstruction and angina pectoris, in traditional Chinese medicine (TCM). Both types of coronary disease are severe and require urgent intervention. The pulse-activating powder formula was taken from a comprehensive TCM book called Medicine Origin. YFP has a beneficial impact on the replenishment of Qi and pulse activation It well nourishes Yin and promotes glandular secretion in TCM theory. The Seattle Angina Scale (SAQ), ECG, stress echocardiography (stress echocardiography, SE) and amino-terminal pro-brain natriuretic peptide precursor (NT-proBNP) were used to assess the efficiency of YFP which was based on pulse-activating powder

Study Design
Treatment
ECG Evaluation
Stress Echocardiography
NT-proBNP
SAQ Scores
Changes of Echocardiography of Patients with IDHF before and after Treatment
Discussions
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