Efficacy of using controlled uterine balloon tamponade for stopping atonic postpartum hemorrhage

Abstract

BACKGROUND: Obstetric hemorrhage remains the leading cause of maternal mortality in Uzbekistan, with uterine atony in the follow-up and postpartum periods being the most common cause.
 AIM: The aim of this study was to evaluate the effectiveness of using uterine balloon tamponade in atonic postpartum hemorrhage.
 MATERIALS AND METHODS: This clinical controlled study was conducted at the Republican Perinatal Center of the Ministry of Health of the Republic of Uzbekistan from 2016 to 2019. Uterine balloon tamponade using a Zhukovsky balloon was used in 50 puerperas with atonic postpartum hemorrhage, of whom 40 women had vaginal delivery and ten patients were delivered by caesarean section. The control group consisted of 50 puerperas with atonic postpartum hemorrhage, traditional therapy being carried out without the use of uterine balloon tamponade, of whom 40 women had vaginal delivery and ten patients were delivered by caesarean section.
 RESULTS: The total volume of blood loss in the main group was lower than in the control group: 998 142 ml vs. 1498 202 ml in vaginal delivery (Students t-test 2.01, p = 0.047563) and 1297 244 ml vs. 1988 226 ml at caesarean section (Students t-test 2.11, p = 0.039463), respectively. Uterine balloon tamponade allowed for stopping postpartum hemorrhage in the blood loss range of 750999 ml and 10001499 ml in 27.5% and 52.5% of cases in the main group and in 20% and 30% of cases in the control group (OR 1.517, 95 % CI 1.5364.293 and OR 2.579, 95% CI 1.0306.457, respectively). When using uterine balloon tamponade, the proportion of massive bleeding with blood loss over 1500 ml was 3.8 times lower than in the control group: 10.0% (5/50) and 38% (19/50), respectively. Hysterectomy due to bleeding was performed in one (2%) postpartum woman in the main group, and in five (10%) puerperas in the control group (OR 0.184, 95% CI 1.0216.133). The use of the tamponade test resulted in a significant decrease in the number of severe bleeding incidents (with blood loss of 1500 ml or more) by 90% during vaginal delivery (OR 0.077, 95% CI 0.0090.635) and elevated the effectiveness of organ-preserving surgeries by 2.9 times, thus increasing the frequency of women with preserved uterus.
 CONCLUSIONS: The effectiveness of uterine balloon tamponade in atonic postpartum hemorrhage was 88.0% (44/50). The simplicity and safety of using uterine balloon tamponade indicates the need for a wider introduction of this technology in postpartum hemorrhages, which will help to reduce their adverse outcomes.