Efficacy of syndrome differentiation of traditional Chinese medicine combined with Mosapride in treatment of functional dyspepsia

Abstract

Objective To explore efficacy of syndrome differentiation of traditional Chinese medicine combined with Mosapride in treatment of functional dyspepsia. Methods 120 cases of functional dyspepsia patients were randomly divided into the two groups,60 cases in each group, patients in the study group were given syndrome differentiation of traditional Chinese medicine combined with Mosapride for treatment, the control group was only given mosapride for treatment. Efficacy, gastric emptying rate after 1h,10h of meal before and after the treatment and adverse reaction of two groups were compared. Results The total effective rate of the study group after treatment was 92.5%,which was significantly higher than 70.0%of the control group(χ2= 7.57,P<0.05);The postprandial gastric emptying rate of the study group after 1h,10h were 38.6%,85.9%, which were significantly higher than 10.3%,29.9%before treatment and 27.8%,68.4%in the control group (χ2=4.34,4.65,4.12,4.23.P<0.05);There was no serious adverse reaction occurred in the two groups of patients. Conclusion Syndrome differentiation of traditional Chinese medicine combined with Mosapride has a significant clinical effect in treatment of functional dyspepsia, which can improve the symptoms and signs of the patients fundamentally, with high security, which is worthy of clinical application. Key words: Functional dyspepsia; TCM syndrome differentiation; Mosapride