Abstract

Predictors of the severity of pain after a thermal trauma vary depending on the phase of the burn wound healing. For the analysis of a homogen eous sample of victims with a deep burn, patients with a total burn injury area of 15.4 ± 4.2%, who underwent autodermoplasty of the skin during 14 daysafter the thermal trauma.Patients were divided in to two groups: first group (n = 30), which in the perioperative period was anesthetized with Sertofen (dexketoprofen trometamol 50 mg / 2 ml 2 ml 3 times a day) in the intensive care complex. The first dose of the drug was administered intraoperatively to prevent analgesia. Fol low-up anesthesia with Sertofen was carried out at 50 mg / 2 ml 2 ml 3 time s a day for 2-3 days postoperative period. Second group (n = 28) – in the nearest postoperative period received a narcotic analgesic (promedol 2% 1 ml), as an analgesia used analgin (metamizole sodium). All patients in the first and second observation groups underwent surgical treatment of skin burns at 12.5 ± 2.8 and 10. 3 ± 2.5 days of burn disease, respectively.It was established that in patients of first group with perioperative anesthesia with Sert fen, was observed more even decrease of pain syndrome, a tendency to lower blood levels of cortisol and stable blood glucose values.It was concluded, that in perioperative period in patients with thermal trauma the use of dexketoprofen trometamol ( Sertofen ), causes effective and safe anesthesia and can be recommended in this group of patients.

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