Abstract

Objective: Neuroendoscopic treatment is an alternative therapeutic strategy for the treatment of septate chronic subdural hematoma (sCSDH). However, the safety and efficacy of this strategy remain controversial. We compared the clinical outcomes of neuroendoscopic treatment with those of standard (large bone flap) craniotomy for sCSDH reported in our center. Furthermore, the safety and efficacy of the neuroendoscopic treatment procedure for sCSDH were evaluated.Methods: We retrospectively collected the clinical data of 43 patients (37 men and six women) with sCSDH who underwent either neuroendoscopic treatment or standard (large bone flap) craniotomy, such as sex, age, smoking, drinking, medical history, use of antiplatelet drugs, postoperative complications, sCSDH recurrence, length of hospital stay, and postoperative hospital stay. We recorded the surgical procedures and the neurological function recovery prior to surgery and 6 months following the surgical treatment.Results: The enrolled patients were categorized into neuroendoscopic treatment (n = 23) and standard (large bone flap) craniotomy (n = 20) groups. There were no differences in sex, age, smoking, drinking, medical history, antiplatelet drug use, postoperative complications, and sCSDH recurrence between the two groups (p > 0.05). However, the patients in neuroendoscopic treatment group had a shorter length of total hospital stay and postoperative hospital stay as compared with the standard craniotomy group (total hospital stay: 5.26 ± 1.89 vs. 8.15 ± 1.04 days, p < 0.001; postoperative hospital stay: 4.47 ± 1.95 vs. 7.96 ± 0.97 days, p < 0.001). The imaging and Modified Rankin Scale at the 6-month follow-up were satisfactory, and no sCSDH recurrence was reported in the two groups.Conclusions: The findings of this study indicate that neuroendoscopic treatment is safe and effective for sCSDH; it is minimally invasive and could be clinically utilized.

Highlights

  • Chronic subdural hematoma (CSDH) refers to subdural hemorrhage, which usually occurs 3 weeks after traumatic brain injury [1]

  • There were no differences in sex, age, smoking, drinking, medical history, antiplatelet drug use, postoperative complications, and septated CSDH (sCSDH) recurrence between the two groups (p > 0.05)

  • The patients in neuroendoscopic treatment group had a shorter length of total hospital stay and postoperative hospital stay as compared with the standard craniotomy group

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Summary

Introduction

Chronic subdural hematoma (CSDH) refers to subdural hemorrhage, which usually occurs 3 weeks after traumatic brain injury [1]. The pathogenesis of CSDH has not been fully elucidated. If the hematoma is surrounded by an envelope, repeated bleeding can occur. A pseudomembrane or fibrous septum in the hematoma cavity can form septations in the hematoma. This can lead to the formation of a septated CSDH (sCSDH) with septate cavities. Four methods are commonly used to treat CSDH: conservative (medical) treatment, twistdrill craniostomy, burr hole evacuation, and large bone flap craniotomy [2, 3]

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