Abstract
V Malizia, S Fasola, G Ferrante. Int Arch Allergy Immunol. 2017;174(2):97–103 In this randomized control trial, buffered hypertonic saline (BHS) nasal rinses were compared with normal saline (NSS) nasal rinses in improving nasal symptoms in pediatric patients with seasonal allergic rhinitis (SAR). From October 2015 to February 2016, 36 children (ages 6–13 years) diagnosed with SAR and having active symptoms per the Total 5 Symptom Score (T5SS) were recruited from a single allergy outpatient clinic in Palermo, Italy. During the screening visit, skin prick tests to grass mix and olive pollen were performed to confirm allergic sensitization to pollens. Children were randomly assigned to either receive daily NSS (0.9%) or BHS (3%). The study began in May 2016, during the pollen season, and subjects were trained to administer (unblinded) 5 mL of NSS or BHS with an …
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