Abstract
Abstract Background Dr DC Janse van Rensburg* MBChB, MMed, MSc Dr L FletcherO PhD ProfM Viljoen* PhD, PhD Ms C Coertzen' BA(MBK) Hons Mrs CC Grant* MSc Dr DA Ramagole* MBChB, MSc Dr RM Collins* MBChB, MSc ProfJA Ker· MBChB, MMed, MD University of Pretoria *Section Sports Medicine °Department of Statistics -'Department of Physiology 'Department of Biokinetics, Sport and Leisure Sciences ·Faculty of Health Sciences Correspondence: Dr DC Janse van Rensburg Section Sports Medicine University of Pretoria POBox 12651 0028 Hatfield Tel: (012) 420-6057 Fax: (012) 362-3369 E-mail: vrensburg@sport.up.ac.za Rheumatoid arthritis (RA) is a chronic, immune-inflammatory disease of unknown aetiology affecting the synovial membrane of joints and surrounding tissues. Typically RA affects both large and small joints in a bilateral, symmetrical, poly-articular fashion. Degradation of bone, cartilage and muscle eventually lead to a reduction in physical function. The purpose of this study was to determine the efficacy of an endurance exercise programme on the fitness parameters (flexibility, strength and aerobic measurements), quality of life (visual analogue scale and health assessment questionnaire) and disease activity (DAS28[4] version with CRP) of female RA padents.
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