Abstract
Objective To study the efficacy of Teprenone in treatment of chronic superficial gastritis in the elderly.Methods 124 elderly patients with chronic superficial gastritis from 2010 to 2012 in our hospital,were selected as research object.They were divided into two groups according helicobacter pylori infection.All patients underwent gastroscopy,using the Teprenone capsule (50 mg,3 times/d) to treat them.The entire treatment needed eight weeks.Results After the treatment,63 of the Hp+ group' s patients improved their symptoms such as nausea,belching,heartburn and acid reflux,the success rate was 92.6％; 50 of the Hp-group' s patients improved their symptoms,the success rate was 89.3％.The result of the gastroscopy,Hp+ group had 37 patients improved (54.4％);Hp-group had 27 patients improved (48.2％).The results showed no statistical significant difference (P＞0.05).Conclusion Teprenone is able to protect the gastric mucosa,it can cure the chronic superficial gastritis in the elderly.But it' s not acid-fast,and can' t kill the helicobacter pylori,if the patients' Hp is positive,it needs other medication for anti-infection. Key words: Teprenone; Elderly; Chronic superficial gastritis
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