Efficacy and Tolerability of Vimpat in Patients with Intractable Epilepsy

Abstract

Epilepsy is a complex neurological disorder caused by abnormal, sudden, excessive electrical discharges of the neurons in the brain. There are many different seizure types and epileptic syndromes, but all involve abnormal electrical activity. It has been shown that 30% of patients with epilepsy remain medically intractable. For these patients, many of whom have failed multiple classes of antiepileptic drugs (AEDs) and/or surgical procedures, newly FDAapproved drugs are of particular interest.