Efficacy and safety of Bi qi capsules in the treatment of cervical spondylosis: an update of the meta-analysis

Abstract

Background: At present, the treatment of cervical spondylosis by traditional Chinese medicine has attracted extensive attention. Studies have found that the efficacy of Bi qi capsules in the treatment of cervical spondylosis is different. Therefore, this study systematically evaluated the efficacy of Bi qi capsules or combined with conventional drugs for the treatment of cervical spondylosis. Meta-analysis of visual pain simulation (VAS) score and adverse reactions. Methods: From 8 databases of CNKI, VIP, Wan fang Data, CBM, PubMed, Web of science, Embase, and Cochrane Library, the data of Bi qi Capsules or combined conventional drugs for cervical spondylosis in the past 10 years from 2012 to July 2022 were retrieved. Randomized controlled trials were conducted to evaluate the efficacy, VAS score and adverse reactions of Bi qi Capsules on cervical spondylosis through a random-effects model system for meta-analysis. Results: Eight studies with 758 participants, 379 in the treatment group and 379 in the control group, were included in this study. Compared with the control group, the effective rate of Bi qi Capsule or combined with conventional drugs for cervical spondylosis was significantly improved, the VAS score was significantly lower than that of the control group, and the occurrence of adverse reactions was not significantly different from that of the control group. Conclusion: Bi qi Capsule is safe and effective in the treatment of cervical spondylosis and can significantly reduce neck and shoulder pain.