Abstract
Background: Postpartum hemorrhage is a life-threatening pregnancy complication and we want to evaluate the safety and efficacy of autologous blood transfusion during cesarean section in women with placenta previa to deal with postpartum hemorrhage. Methods: We conducted a retrospective study concentrating on all cases of placenta previa using autologous blood recovery during cesarean section in a single-center from August 2016 to July 2018, and then grouped and compared the clinical and patient characteristics. Linear regression analysis was conducted to analyze the linear relationships between estimated blood loss and recovered autologous blood volume, recovered autologous blood volume and transfused autologous blood volume, and transfused autologous blood volume and estimated blood loss. Results: In our study, autologous blood recovery technology was used during cesarean section for 294 patients with placenta previa, and a total of 266,660 mL of blood was collected and 134,342 mL of autologous blood was transfused, saving 746 U of red blood cell suspension. Recovered and transfused blood volumes were higher in patients with suspected placenta accreta and resection of the uterus. There were no serious adverse reactions related to autologous blood recovery and transfusion. Conclusions: The use of autologous blood transfusion during cesarean section in patients with placenta previa is safe and can save blood resources.
Highlights
Postpartum hemorrhage is a life-threatening pregnancy complication and is one of the most common causes of maternal death with about 166,000 deaths from obstetric hemorrhage worldwide every year [1]; it is the leading cause of maternal death in China
In 2015, China implemented the second-child policy nationwide. This resulted in an increase in the number of pregnant women with advanced age, pregnancies in women with a scarred uterus, pregnancy comorbidities such as placenta accreta, placenta previa, and placental abruption, increasing the risk of massive hemorrhage
Intraoperative cell salvage (IOCS) was used with 294 patients and 266,660 mL of blood was collected while 134,342 mL of autologous blood was transfused
Summary
Postpartum hemorrhage is a life-threatening pregnancy complication and is one of the most common causes of maternal death with about 166,000 deaths from obstetric hemorrhage worldwide every year [1]; it is the leading cause of maternal death in China. In 2015, China implemented the second-child policy nationwide This resulted in an increase in the number of pregnant women with advanced age, pregnancies in women with a scarred uterus, pregnancy comorbidities such as placenta accreta, placenta previa, and placental abruption, increasing the risk of massive hemorrhage. Postpartum hemorrhage is a life-threatening pregnancy complication and we want to evaluate the safety and efficacy of autologous blood transfusion during cesarean section in women with placenta previa to deal with postpartum hemorrhage. Methods: We conducted a retrospective study concentrating on all cases of placenta previa using autologous blood recovery during cesarean section in a single-center from August 2016 to July 2018, and grouped and compared the clinical and patient characteristics. Conclusions: The use of autologous blood transfusion during cesarean section in patients with placenta previa is safe and can save blood resources
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