Effects of Vitamin C and E on lipid profile and kidney performance of Albino Rats

Abstract

The current study has been intended to estimate the belongings of vitamins E and C on lipid profile and renal performance of Albino rats. Vitamin E is a chain-breaking lipid dissolvable cancer prevention agent that has been utilized in the therapy of cardiovascular illnesses, immunological and hematological issues, and peripheral neuropathy. Vitamin C is enormous in imperative metabolic exercises including tryptophan digestion, iron retention, development of ferritin as cell cancer prevention agent, electron transport framework and coenzyme for cathepsin, liver esterases, and omega-oxidation of unsaturated fats. Vitamin C and E are known to be powerful antioxidant, utilization of vitamin C and E indicated significantly lowered hypertension and improved insulin activity, and decline lipid profile. Both vitamin C and vitamin E decreased lipid peroxidation. The experiment was conducted on Albino rats and treated with different doses of vitamins according to the protocol. Albino rats were divided into 4 groups, out of four groups one group was called the control group and the other 3 groups were treated groups, treated group A was supplemented with vitamin C, treated group B was supplemented with vitamin E), treated group C was supplemented with both vitamins together and fourth group (Group D) called the control group this group was given free access to food and water throughout the experiment. After completion of the experimental period, rats were sacrificed for the collection of blood, and blood was taken in EDTA for the collection of serum. Serum was collected for the analysis of higher density lipoprotein test (HDL), low-density lipoprotein (LDL), very low-density lipoproteins test (VLDL), total cholesterol test (TG), meanwhile Urea test, Uric acid test, and Creatinine test were examined. Results showed that means values of initial body weight and final body weight were significantly (p≤0.05) different. Values of Liver, Kidney, Pancreas, and Heart weight (g) of Albino rats were significantly (p≤0.05) different. Values of Urea, Uric acid, and Creatinine of Albino rats were significantly (p≤0.05) different. Values of the lipid profile of Albino rats were significantly (p≤0.05) different.