Abstract
Objective To compare the effect of percutaneous vertebroplasty (PVP) in the treatment of osteoporotic vertebral compression fractures (OVCF) by using high - viscosity polymethylmethacrylate (PMMA) cement and low-viscosity PMMA cement, and to provide theoretical basis for clinical PVP in the future. Methods The clinical data of 158 OVCF patients, who underwent PVP between January 2014 and January 2015 , were retrospectively analyzed. According to the viscosity of the cement used in PVP, the patients were divided into high-viscosity group (n=75, group A) and low-viscosity group (n=83, group B). The visual analogue scale (VAS) and Oswestry dysfunction index (ODI) were used to evaluate the pain scores and spine function scores, respectively. The incidences of bone cement leakage and adjacent vertebral fracture were compared between the two groups. Results The follow-up time ranged from 12 to 18 months with an average follow-up of (14.3±3.6) months. There were no statistically significant differences in age, sex ratio, body mass index (BMI) , bone mineral density (BMD) , VAS score and ODI between the two groups (P>0.05 ). The VAS and ODI at 3d after the operation and the last follow- up decreased in the two groups compared with those at the baseline (P 0.05 ) . The leakage rate in group A (9.3%) was significantly lower than that in group B (25.3%) (P 0.05 ) . No other complications were found in the two groups. Conclusion Both high- viscosity and low- viscosity bone cements are effective in treating OVCF. The leakage rate of using high-viscosity bone cement is significantly lower than that of using low-viscosity bone cement, which shows significantly advantages. Key words: Vertebroplasty; Cement leakage; Vertebral fracture; Osteopomsis; Bone cement
Published Version
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