Abstract

Background Phosphodiesterase-5-inhibitors are vasoactive drugs used in the treatment of erectile dysfunction and pulmonary hypertension. Their beneficial effects in the pulmonary vasculature are widely described, but it remained unclear, how they influence cardiac performance. In the present study we investigated the effects of the phosphodiesterase5-inhibitor vardenafil on myocardial and vasomotor function in a rat model.

Highlights

  • Open AccessA selective phosphodiesterase-5-inhibitor, on cardiovascular function in a rat model

  • Phosphodiesterase-5-inhibitors are vasoactive drugs used in the treatment of erectile dysfunction and pulmonary hypertension

  • 3rd International Conference on cGMP Generators, Effectors and Therapeutic Implications Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here.

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Summary

Open Access

A selective phosphodiesterase-5-inhibitor, on cardiovascular function in a rat model. Published: 25 July 2007 BMC Pharmacology 2007, 7(Suppl 1):P39 doi:10.1186/1471-2210-7-S1-P39. 3rd International Conference on cGMP Generators, Effectors and Therapeutic Implications Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here.

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