Abstract
Effects of UVA+UVB Solar Radiation Levels and Cross-Linking on Animal Model with Bowman’s Layer: Chicken
Highlights
Eyes are regularly and continuously exposed to sunlight
Cell death affected the whole thickness of stroma in the UVA+Ultraviolet B CXL (UVB) group and anterior and middle stroma in CXL
Fluorescein testing was positive in the UVA+UVB group 24 hours post-treatment and every day until 2 ± 0.9 days after the last dose of radiation
Summary
Eyes are regularly and continuously exposed to sunlight. Solar radiation is composed of ultraviolet (UV) radiation: UVA (320-400 nm), UVB (280-320 nm), UVC (100-280 nm) and visible light (400700 nm). On the Earth’s surface, UV radiation consists mainly of UVA (97%) and UVB (3%) wavelengths [1,2]. The absorption of solar radiation by different corneal layers is related to the wavelength. The cornea, aqueous humor and lens absorb UVA radiation, whereas the cornea primarily absorbs UVB radiation. The epithelium and Bowman’s layer absorb 2 to 2.75 times more UV radiation up to 300 nm of wavelength (UVB) than the stroma [5,6]. UVB is the smaller part of the UV environmental radiation, it is the most harmful [5,6]
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