Abstract
A total of 107 vitiligo patients were randomly divided into 3 groups.Group A received an intralesional injection of Bacillus Calmette-Guerin-polysaccharide nucleic acid (BCG-PSN) (n=34), group B Compound Glycyrrhizin Tablets (n=36) and group C both (n=37). Before treatment and 3 months after treatment, cellular immune function was detected for each group.Paired comparisons of 3 groups before and after treatment showed that CD4+ , CD4+ /CD8+ ratio increased (all P<0.05) and CD8+ decreased (P<0.05). After treatment, as compared with groups A and B, CD4+ increases (both P<0.05) and CD8+ decreased in group C (P<0.05). Group C had an efficiency rate of 91.9% and it was higher than the other two groups (both P<0.05). An intralesional injection of BCG-PSN plus Compound Glycyrrhizin Tablets could improve immune function and treat vitiligo patients efficiently. Key words: Vitiligo; Cellular immunity
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