Abstract
Encephalopathy of prematurity is still an important reason which affects the survival and quality of life of preterm infants.During hospitalized in neonatal intensive care unit (NICU), a variety of environmental factors such as noise, light, too much tactile stimuli, pain, and maternal-infant separation all will affect the development of preterm infants' brain, leading to encephalopathy of prematurity.Therefore, need to attach importance to the effects of NICU environment on the growth and development and the neurological function of preterm infants, try to optimize the environment of NICU, to reduce the incidence of brain injury of prematurity, improve the long-term prognosis of preterm infants. Key words: Encephalopathy of prematurity; Neonatal intensive care unit; Noise; Light; Tactile stimulus; Pain; Maternal-infant separation
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