Abstract
ITUATED deep within the paramedian region of the cerebellum lies a constellation of nuclei that relay cerebellar influences throughout the central nervous system. The dentate, which is the largest of these nuclei in man, was first described in 1685 by VieussenY 9 It relays chiefly the efferent outflow from the lateral hemispheric area of the cerebellum, exerting its influence on the tone and movement of the ipsilateral limbs. 1,~,~4,25 Experimental dentate lesions result in hypotonia, dysmetria, and, in some cases, tremor. 1,~,24 Recently, neurosurgeons have attempted to ablate the dentate in persons with extreme hypertonia and involuntary movements. We have developed stereotaxic coordinates for the cerebellar nuclei in order to explore the paramedian cerebellar regions by electrical stimulation with a view of assessing the therapeutic possibilities of cerebellar nuclear lesions. 26 This report concerns the effects of electrical stimulation and high frequency lesions in the regions of paramedian cerebellar structures. Method
Published Version
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