Abstract
OBJECTIVE: In this study, the effects of sperm parameters on the success of intrauterine insemination were investigated. STUDY DESIGN: The data from 309 infertile couples who were admitted between 2012-2018 without a female factor were analyzed retrospectively and included in the study. After the administration of gonadotropin and hCG (5000-10000 IU), single insemination was performed in 36-40 hours in all cycles. All couples underwent routine infertility screening. The relationship between sperm parameters (motility, morphology, sperm count), patient age, duration of infertility with intrauterine insemination success was evaluated.RESULTS: There was no statistically significant difference between the two groups in terms of mean age and age related-parity. There was no statistically significant difference between male ages, liquefaction, and sperm volumes between the two groups (p=0.898, p=0.448, p=0.651). Before washing; There was a statistically significant difference between the sperm concentration, percentage of total motile sperm, percentage of progressive motility sperm, percentage of normal sperm morphology, and total sperm count between the two groups (p=0.0001, p=0.0001, p=0.0001, p=0.0001, p=0.0001). After sperm washing; the results were similar to those obtained before washing. While statistically significant difference was observed between sperm volume and sperm concentrations (p=0.023, p=0.018), no significant difference was observed between the two groups in total sperm count (p=0.612).CONCLUSION: As a result, during the application of intrauterine insemination to infertile couples, total motile sperm count, progressive motility sperm count ratio and high sperm ratio with normal morphology used in order to increase pregnancy success can be considered as criteria that increase the chances of success.
Highlights
While statistically significant difference was observed between sperm volume and sperm concentrations (p=0.023, p=0.018), no significant difference was observed between the two groups in total sperm count (p=0.612)
As a result, during the application of intrauterine insemination to infertile couples, total motile sperm count, progressive motility sperm count ratio and high sperm ratio with normal morphology used in order to increase pregnancy success can be considered as criteria that increase the chances of success
A statistically significant difference was observed between sperm concentration, percentage of total motile sperm, percentage of progressive motility sperm, percentage of normal sperm morphology, and total sperm count between both groups (p=0.0001, p=0.0001, p=0.0001, p=0.0001, p=0.0001 (Table II)
Summary
Effects of Sperm Parameters on Pregnancy Rate in Patients Undergoing Intrauterine Insemination. Male reproductive dysfunctions are responsible for almost up to 50% of infertility cases [2]. Intrauterine insemination (IUI) is one of the methods used in the treatment of infertility as it is cheaper, simpler and less invasive than other assisted reproductive techniques (ART). Sperm preparation methods, and sperm count and motility during insemination are important parameters that may affect IUI and pregnancy rates. When the literature is reviewed, significant differences are observed between these parameters and pregnancy rates [3]. IUI is a widely used reproductive technology method in the world, the effect of various sperm characteristics on pregnancy rate is still controversial.
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