Effects of Specific Power-Loss on the Characteristics of Temperature in Magnetic Nanoparticles Subjected to External Alternating Magnetic Fields

Abstract

The variation of the specific power-loss with the anisotropy constant takes an approximately exponential form when magnetic nanoparticles (MNPs) are subjected to external alternating magnetic fields, and the distribution of the specific power-loss along the anisotropy constant shifts with temperature. Furthermore, the rate of increase in the temperature of MNPs used for hyperthermia depends significantly on the specific power-loss. Hence, the temperature characteristics of hyperthermia are affected by the specific power-loss. In this work, we develop a thermal model to analyze the effect of specific power-loss on temperature characteristics in MNPs uses for tumor hyperthermia. The results predicted by using the thermal model in this study are consistent with the available experimental data. The rate of increase of the temperature evidently varies at different temperatures due to different specific power-losses. An abrupt temperature rise occurs at the highest value in the distribution of the specific power-loss versus anisotropy constant. On the other hand, a slow temperature rise occurs when the intersection between the anisotropy constant of the MNPs and the specific power-loss distribution along the anisotropy constant at a some certain temperature corresponds with low specific power-loss.